A Pechmann condensation between the appropriate keto ester and
'- Part 2
The smoking of marijuana initiates many processes in the body, mind and even soul, depending upon the
intent with which it is used. In Part 1 many of these were mentioned in passing, and will be Early Bud explored in
some detail in this issue. It is very important for people to understand that marijuana, like other teacher
plants, is properly called an �entheogen� or �agent in God�, as a psychoactive substance with spiritual
reason it appeals to common sense. The truth is
the drug need not retain that mixture of fear, awe, and excitement in use to retain its
appeal. Experienced users become comfortable with the marijuana high, much as they
might enjoy making love with a spouse of long duration. By losing much of its
subterranean character, marijuana does not necessarily lose its appeal. In fact, whatever
uncomfortable or even psychotomimetic effects the drug might have had earlier, with
limited experience, become dissipated with increased use. In general, experienced users
describe their high in more favorable terms than the inexperienced. (Although individuals
who do experience discomfort in use tend to discontinue smoking.) Simultaneously, the
experience becomes increasingly less and less "apart" from the everyday, less and less
discontinuous with it, and increasingly a normal and taken-for-granted element in one's
day to day existence.
Among the more experienced users, marijuana comes to be regarded as an ordinary
item in one's life—it becomes "no big deal." In fact, users of long duration have a difficult
time switching back and forth from their taken-for-granted attitude toward pot to society's
(13 of 15)4/15/2004 1:05:28 AM
The Marijuana Smokers - Chapter 6
fearful and punitive stance. Many users do not regard marijuana as a drug—i.e., in a
special and distinct and harmful category—just as few liquor drinkers will claim to be
users of any drug, so unaccustomed are they to thinking of their drug of choice as
anything of particular note. During the research, I went into a psychedelic book store in
New York's East Village and asked the salesman, wearing long hair, beads, and bells and
sandals, if they had any books on drugs. "What kind of drugs?" he asked. When I said
marijuana, he replied, "Marijuana's not a drug." This theme emerged in the interviews. A
twenty-three-year-old woman, a daily smoker of marijuana, told me, "I can't think of
marijuana as being a drug—it's just pleasurable."
N O T E S
1. Howard S. Becker, "Becoming A Marihuana User," American Journal of Sociology
59 (November 1953): 235-243. (back)
2. In a study of the drug use of 432 "Yippies" in Chicago's Lincoln Park at the time of
the 1968 Democratic National Convention, Zaks, Hughes, Jaffe, and Dolkart found that
the most common reason claimed by the respondents for "starting on drugs" (i. e., for
turning on)—marijuana was by far not only the most popular drug, but was most likely to
have been the first drug used—was that he was turned on by friends; almost two-thirds of
the sample (63 percent) gave that as their reason. (Cf. Table 6, p. 24.) Without an
understanding of this process, this answer might seem a non sequitur. But the fact that a
friend (whose judgment we trust) gives us an opportunity to try a drug has a great deal to
do with whether we ever turn on or not. An additional fifth of the sample (22 percent)
gave "association with users" as a reason g high, under
(2 of 9)4/15/2004 1:08:52 AM
The Marijuana Smokers - Chapter 12
the influence of the drug, is thought to be by definition abnormal. This view holds that
marijuana intoxication is such that reality is distorted: the subject feels euphoric (in
clinical terms, "where there is no objective basis for euphoria"); he often emits
unmotivated laughter; his sense of time is elongated (that is, he judges time "incorrectly,"
or his sense of time is "distorted"); he thinks he hears music more acutely; he thinks food
tastes better; he has illusions of a superior aesthetic sense; and so on. In other words,
according to the pathology model, what is felt and perceived under the influence of a drug
which differs from the normal or nondrug state is in and of itself abnormal and
pathological. In addition, it is an essential tenet of the pathology model that marijuana
tends to induce temporary insanity, "psychotic episodes," in some users.
Moral positions are often justified on rational grounds. To admit that one or another
point of view is merely a matter of taste is rarely sufficient, particularly to someone who
struggles for moral and ideological dominance. A common strategy to discredit other
points of view is to adopt a health-pathology model of justification. One's own ideology
represents mental or physical health, while that of one's opponents is pathological. Some
of the best examples of this variety of rationalization may be found in the area of sexual
behavior. To the sexually permissive, indulgence is normal, and abstinence is sick. To the
supporters of abstinence, it is precisely the reverse:
What is the right thing for the young unmarried woman? The physician is
not a religious teacher and he does not speak on grounds of morality. He
speaks from the standpoint of health, which includes emotional health.
From this standpoint I submit that the desirable ideal is premarital chastity.
The physician stands in excellent relation to society to make such judgments. He has
sufficient scientific credentials in the public eye as well as great prestige, to command
credibility. Moreover, his views are not markedly out of line with those of the majority, so
that he may be useful as a means to justify and rationalize many traditional values,
employing a rhetorical or scientific rationality.
The sociology of medicine is one of the more fascinating the field has to offer. The
illness and health of the human body are social definitions, not simply natural categories.
Even death has a social dimension; it is not only a physiological fact. What is conceived
of as a matter for appropriate medical attention is decided by doctors, not by the human
body. What the body is thought to do, and what is thought to be the cause of what it does,
varies from society to society, from epoch to epoch. What attracts a physician's attention
at one time may be of no concern at another—either because of a change in moral climate
or becau Fahrenholtz, M 7
232 The Total Synthesis of Cannabinoids
During their studies on cannabielsoin (152) Uliss et al Low feelings are rightly
understood as being of low vibration, (such as depression) while high feelings are accurately referred to
as being or �higher vibration�, (such as those states such as happiness, elation, �peak� experiences�, joy,
orgasm, etc.). It is not at all difficult for even the beginning smoker to clearly feel the fact that smoked
marijuana is of a high vibration.
A similar sequence was used for the synthesis of analogs
208, except that during the debenzylation step the double bond was also
reduced istically finds his movement seems exceptionally well
coordinated: "When I move about or dance, my motions seem exceptionally
smooth and well coordinated" (7%, 9%, 28%, 33%, 20%). This is reported
as occurring more frequently by females (p <.05) and by Non-users of
Psychedelics (p <.
It begins to occur at Moderate to Strong levels of
intoxication (7%,31%, 37%, 13%, 1%), with Weekly users needing to be more intoxicated than Occasional or
Daily users for this (p <.05, overall).
The converse effect, "When I move about or dance, my motions seem awkward and uncoordinated" is
infrequent (25%, 31%, 27%, 8%, 5%). It may begin to occur from Moderate Levels of intoxication and higher
(7%, 17%, 19%, 17%, 8%). It is reported as occurring less frequently by Light Total users (p <.05, overall),
Occasional users (p <.05, overall), and Non-users of Psychedelics (p <.01). The Professionals need to be more
intoxicated to experience
harvest cannabis this awkwardness (p
< .05). It is an important research problem to determine whether
this is an actual decrement in coordination or simply an altered perception of one's own movements, possibly
related to time alterations.
A more extreme version of poor coordination is "My sense of balance gets very erratic, making it seem
difficult to walk or even maintain a sitting position." This is a fairly frequent effect (29%, 35%, 28%, 6%, 1%)
in that few users have not experienced it at all, but even fewer experience it Very Often or Usually. It is
reported as occurring more frequently by females (p <.05). It generally occurs at Very Strong levels of
intoxication (2%, 4%, 11%, 35%, 14%), with older users having to be less intoxicated to experience it (p <.
(5 of 15)4/15/2004 7:16:11 AM
On Being Stoned - Chapter 11
Figure 11-4. QUALITY OF MOVEMENT
Note.—For guide to interpreting the "How Stoned" graph,
see note on Figure 6-1.
The relationships between these three
effects on the quality of movement are plotted
in Figure 11-4. Movement seeming
exceptionally well coordinated occurs
significantly more frequently than movement
being uncoordinated and jerky (p <<.
than the sense of balance being lost (p
<<<.0005). There is no significant difference
in frequency of occurrence between
awkwardness and erratic balance.
smoothness of movements occurs at lower
levels of intoxication than awkwardness (p
<.0005) and, in turn, awkwardness occurs at
lower levels of intoxication than balance
becoming lost (p < .
marijuana intoxication seems at first to make
movements feel smoother and more
coordinated, but at very high levels of
intoxication this may reverse and may
sometimes culminate in experiential loss of
the sense of balance.
PERCEPTION OF INTERNAL PROCESSES
Shape of the Body and Location of the Self
We shall first consider an infrequent effect that stands as a bridge between the perception of the ordinary
body with modifications and
effet du cannabis
a more radical shift toward new Padwa and G
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condensation with the appropriate diamine followed by thermal ring closure in
vacuum gave 233
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Tried Mylar this year for the 1st
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P" For example, when ~l-THC is given at a dose of 0 When aroused, ataxia is
evident for 3 to 4 hours after the injection A similar sequence was used for the synthesis of analogs
208, except that during the debenzylation step the double bond was also
reduced hv &'y: LiAlH This "Haze #19" plant is definitely NOT what you would expect phenotype-wise (looks indica), but on the other
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(fruity when growing, spicy "Vicks vapo rub" when cured), it is finicky about its feeding regimen (it immediately
goes yellow)... all traits that one does not associate with Indica.
Not a "wonder" plant, I would rate it 7.5 overall, but its a compact plant, short in height and flowering time, and
you still get a sativa-style of high with an agreeable, non-skunky taste. Good breeding material, good structure
and flowering time, with a respectable high.Adam Tripper